Hello Thong,
When you have large element size the diffusion coefficient is not so important because it is often hidden by the numerical diffusion of advection schemes. A value of 1 to 2 m2/s is reasonable but if in doubt you can use the k-epsilon model, however the latter uses velocity gradients which can be underestimated if the mesh size is too large.
I am just worried that you want to model a salt intrusion with 2D, because it is a typically 3D phenomenon, with a salt wedge going up the river on the bottom, with fresh water above, and this can only be reproduced by Telemac-3D. The only phenomenon that can be taken into account in Telemac-2D with salt is the horizontal gradients of density (sometimes important, like in the North sea in Europe).
With best regards,
Jean-Michel Hervouet