Hello,
No, this has not been done yet in Sisyphe. If you already have the zones in Telemac-2D, a quick and dirty solution would be to change one of the subroutines in Sisyphe corresponding to 1 transport formula, and to change it, adding the command USE DECLARATIONS_TELEMAC2D, ONLY : ZONES,NZONE
Then you can apply different laws by looking at the value of ZONE%I(I) for a point I in the mesh.
This cannot be done in a clean solution because Sisyphe may be compiled without Telemac-2D.
With best regards,
Jean-Michel Hervouet